For years, Blade has fought against the vampires in the cover of the night. But now, after falling into the crosshairs of the FBI, he is forced out into the daylight, where he is driven to join forces with a clan of human vampire hunters he never knew existed—The Nightstalkers. Together with Abigail and Hannibal, two deftly trained Nightstalkers, Blade follows a trail of blood to the ancient creature that is also hunting him—the original vampire, Dracula.
Wesley Snipes
Eric Brooks / Blade
Jessica Biel
Abigail Whistler
Ryan Reynolds
Hannibal King
Kris Kristofferson
Abraham Whistler
Dominic Purcell
Dracula / Drake
Parker Posey
Danica Talos
Natasha Lyonne
Sommerfield
James Remar
Ray Cumberland
John Michael Higgins
Dr. Edgar Vance
Patton Oswalt
Hedges
Callum Keith Rennie
Asher Talos
Paul Levesque
Jarko Grimwood
Françoise Yip
Virago
Mark Berry
Chief Martin Vreede
Paul Anthony
Wolfe
Michael Anthony Rawlins
Wilson Hale
Ginger Page
Zoe
Eric Bogosian
Bentley Tittle
Erica Cerra
Goth Vixen Wannabe
Shannon Powell
Woman Bystander
Birkett Turton
Dingo
Brian Steele
Drake Creature (uncredited)
Christopher Heyerdahl
Caulder
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