After one short blind date, Mary Horowitz, a brilliant and eccentric crossword constructor, is convinced that Steve, a CCN cameraman, is her soul mate. Because his job takes him hither and yon, she crisscrosses the country following Steve, with the encouragement of a reporter, turning up at media events he's at to convince him they are perfect for each other. Along the way, she befriends an assortment of misfits who accept her for who she is, leading her to reassess her reasons for this strange journey.
Bradley Cooper
Steve
Sandra Bullock
Mary Horowitz
Thomas Haden Church
Hartman
Ken Jeong
Angus
Katy Mixon
Elizabeth
DJ Qualls
Howard
Keith David
Corbitt
Howard Hesseman
Mr. Horowitz
Beth Grant
Mrs. Horowitz
M.C. Gainey
Norm the Truck Driver
Jason Jones
Vasquez
Carlos Gómez
Rescue Supervisor
Holmes Osborne
Soloman
Delaney Hamilton
Little Deaf Girl
George Sharperson
Rescuer
Luenell
Protestor Lydia
Christina Carlisi
Teacher
Joe D'Angerio
ABC News Producer
Shanda Laurent
Bus Driver
Kerri Kenney
Miss Hancock
Stephanie Venditto
KNYT Reporter
P.J. Marino
KNYT Sound Tech
Wayne Grace
Retired Mine Supervisor
Noah Munck
Large Kid
Bridget Shergalis
Mini-Mary
James Martin Kelly
Mine Safety Expert
Andrew Lewis Caldwell
Young Rescuer
Bryan Moore
Assistant
Rachel Sterling
Booby Botanist
Jackie Johnson
CCN Meteorologist
Regino Montes
Maintenance Guy
Elliott Cho
Daniel
Justin Grafman
Deaf Boy
Joy Darash
Hipster Girl
Jordan Green
Kid
Geraldo Rivera
Self
Beverly Polcyn
Old Lady
Misha DiBono
Paula
Vernard 'Bone' Hampton
Security Guard
Hari Kondabolu
Crossword Businessman
Jordan Morris
Protestor Winston
Dorie Barton
Horowitz House Reporter #1
Patrick Brown
Horowitz House Reporter #2
Alvera DeLeon
Horowitz House Reporter #3
Gillian Vigman
Misc. (Female) News Reporter
Michael Joseph Carr
BBC Reporter
Larry Dorf
MSNBC Reporter
Darcy Fowers
Guest Expert
Lo Mutuc
Young Protester
Tyrone Giordano
Dad
Hollie Stenson
Another Reporter
Kurt Ela
Reporter #1
Kelli Kirkland
Receptionist
Lucy Davis
Patient
Hira Ambrosino
Mrs. Yamamoto (uncredited)
Jonathan Chase
Gregg (uncredited)
Andre Alexsen
Colorado State Trooper (uncredited)
Nick Hodaly
CCN Arabic News Anchor (uncredited)
Sara Sanderson
Houston Anchor (uncredited)
Martin Dew
Reporter (uncredited)
Ken Edling
Reporter (uncredited)
DeeDee Bigelow
Saloon Gal (uncredited)
Rebecca Hyland
Crap Game Stick Woman (uncredited)
Eddie Jemison
Psychiatrist with Crossword Puzzle (uncredited)
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