Charlie and Dan have been best friends and business partners for thirty years; their Manhattan public relations firm is on the verge of a huge business deal with a Japanese company. With two weeks to sew up the contract, Dan gets a surprise: a woman he married on a drunken impulse nearly nine years before (annulled the next day) shows up to tell him he's the father of her twins, now seven, and she'll be in jail for 14 days for a political protest. Dan volunteers to keep the tykes, although he's uptight and clueless. With Charlie's help is there any way they can be dad and uncle, meet the kids' expectations, and still land the account?
John Travolta
Charlie
Robin Williams
Dan
Kelly Preston
Vicki
Conner Rayburn
Zach
Ella Bleu Travolta
Emily
Lori Loughlin
Amanda
Seth Green
Ralph White
Bernie Mac
Jimmy Lunchbox
Matt Dillon
Yancy Devlin
Dax Shepard
Gary - Child Proofer #1
Luis Guzmán
Nick - Child Proofer #2
Ann-Margret
Martha
Rita Wilson
Gloria Lawrence
Justin Long
Troop Leader Adam
Amy Sedaris
Condo Woman
Residente
Tattoo Artist
Sab Shimono
Yoshiro Nishamura
Kevin Yamada
Riku
Kevin Dean-Hackett
Tijuana Priest
Laura Allen
Kelly
Sam Travolta
Singing Waiter
Margaret Travolta
Singing Hostess
Nick Loren
Singing Waiter 2
Kenneth Maharaj
Indian Guy
Nova Mejia
Hot Waitress
Margaret Goodman
Grandma
Jerome Weinstein
Grandpa
Allie Woods Jr.
Old Guy
Michael Enright
Singing Waiter 3
Alexa Havins
Hot Waitress 2
Keenan Shimizu
Japanese Executive
Akira Takayama
Japanese Executive
Shirô Oishi
Japanese Executive
Yoshio Mita
Japanese Executive
Seiji Kakizaki
Japanese Executive
Keisuke Jim Nagahama
Japanese Executive
Costas Panay
Little Kid
Kate Lacey
Rayburn & Reed Employee
Denise Violante
Spanish Lady
Tonia-Marie Gallo
Lazy Pooch Employee
Chika Kanamoto
Japanese Flight Attendant
Marcel Becker
Waiter
Alison Pelletier
Hot Waitress 3
Dylan Sprayberry
Cute Soccer Kid
Bradley Steven Perry
Soccer Kid
Joey Pordan
Soccer Kid
Jason Davies
Dancer
Alicia Mazepa
Dancer
Marielys Molina
Dancer
Charlene Smith
Dancer
Tera Lee Pollin
Dancer
Brendan King
Dancer
Jason Dougherty
Dancer
Kevin Aubin
Dancer
Christine L. Anderson
Back-Up Singer
Crystal MacKenzie
Back-Up Singer
Erynn Dickerson
Back-Up Singer
Noel MacNeal
Muppet
John E. Kennedy
Muppet
Matt Vogel
Muppet
Josh Cohen
Muppet
Bruce Connelly
Muppet
Joe Kovacs
Muppet
Tom Woodruff Jr.
Gorilla
DeRay Davis
Zoo Security Guard
Paulo Costanzo
Zoo Maintenance
Chris J. Cullen
Pretzel Man (uncredited)
Kendall Draughn
Ice Cream Girl (uncredited)
Steve Ferrarie
Pedestrian (uncredited)
Catherine Fetsco
Hot Jogger (uncredited)
Ingrid Johnson
Big Tina (uncredited)
Yulia Klass
Restaurant Patron (uncredited)
Heland Lee
Japanese Security Guard #1 (uncredited)
Jian Leonardo
Airport Security #3 (uncredited)
Jeffrey Mowery
Commuter (uncredited)
Panama Redd
Singing Waiter (uncredited)
Hector Rodriguez Jr.
Commuter (uncredited)
Harry L. Seddon
Businessman (uncredited)
Melissa Silver
Bartender (uncredited)
Frank Tedesco
South Beach Dude (uncredited)
Nina Vincent
Conga Line Dancer (uncredited)
Eden Wright
Girl at Birthday (uncredited)
John Saxon
Lee Robinson
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