For burger-joint employee Tammy, a bad day keeps getting worse. She wrecks her car, loses her job, and finds that her husband has been unfaithful. It's time to hit the road, but without money or transportation, Tammy's options are limited. Her only choice is a road trip with her hard-drinking grandmother Pearl, who has a car, cash, and an itch to see Niagara Falls. It's not the escape Tammy had in mind, but it may be what she needs.
Melissa McCarthy
Tammy
Susan Sarandon
Pearl
Kathy Bates
Lenore
Mark Duplass
Bobby
Gary Cole
Earl
Allison Janney
Deb
Dan Aykroyd
Don
Sandra Oh
Susanne
Nat Faxon
Greg
Toni Collette
Missi
Ben Falcone
Keith Morgan
Sarah Baker
Becky
Rich Williams
Larry
Steve Little
Jet Ski Rental Guy
Dakota Lee
Kathleen
Mark L. Young
Jesse
Mia Rose Frampton
Karen
Steve Mallory
Cashier
Big Al Hall
Possum Creek Bluegrass Band
Jones Smith
Possum Creek Bluegrass Band
Joe Baxter
Possum Creek Bluegrass Band
Benjamin Chontos
Possum Creek Bluegrass Band
Sean Gould
Possum Creek Bluegrass Band
Keith Welborn
DJ
Oscar Gale
Javier
Justin Smith
Paramedic
Willie Hill
Prison Guard
Zach Hanner
Man at Blue Post Bar-B-Que
Jason Vail
Man at Blue Post Bar-B-Que
Leon Lamar
Old Man with Walker
Larry Dorf
Officer Mannis
Ricky Muse
Officer Curtis
Barbara Weetman
Officer Carty
William Flaman
La Grange Bail Cop
Rey Hernandez
Cop at Lakehouse
Penn Holderness
News Anchor
Michelle Li
News Reporter
Raven Angeline Whisnant
Charlotte
Damon Jones
Jerry Miller
Sandy McCarthy
Old Lady Leaving a Bar
Margo Passas
Old Lady Leaving a Bar
Rob Springer
Gene the Cook (uncredited)
Kaitlyn Christian
Canoe Teen (uncredited)
J.R. Rodriguez
Kentucky Trooper (uncredited)
Michelle Rivera Huckaby
Arresting Cop (uncredited)
David Andrew Nash
Morningside Guard (uncredited)
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