Michael and Sara wed, but the happiness is short-lived when the Feds apprehend her for the murder of Michael's mother, Christina. Once a hit is ordered on Sara, the team reunite to break out the increasingly vulnerable target.
Wentworth Miller
Michael Scofield
Sarah Wayne Callies
Sara Tancredi
Dominic Purcell
Lincoln Burrows
Jodi Lyn O'Keefe
Gretchen Morgan
Amaury Nolasco
Fernando Sucre
Robert Knepper
Theodore 'T-Bag' Bagwell
William Fichtner
Alex Mahone
Leon Russom
Jonathan Krantz
Amy Aquino
Warden Alice Simms
Lori Petty
Daddy
Kim Coates
Agent Richard Sullins
Barbara Eve Harris
FBI Agent Felicia Lang
Chris Bruno
Agent Todd Wheatley
David Starzyk
Blue Phillips
Aisha Hinds
Guard Cowler
Jeff Cahill
Snee
Dendrie Taylor
Blonde Guard
Damien Leake
Detective Marlin
Livia Treviño
Hucks
Alicia Lagano
Agatha
Dot-Marie Jones
Skittlez
Kathleen Quinlan
Christina Rose Scofield
Adrienne McQueen
Prison Guard (uncredited)
'Big' LeRoy Mobley
Hotel Security Guard (uncredited)
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