The hilarity begins when professor Sherman Klump finds romance with fellow DNA specialist, Denise Gaines, and discovers a brilliant formula that reverses aging. But Sherman's thin and obnoxious alter ego, Buddy Love, wants out...and a big piece of the action. And when Buddy gets loose, things get seriously nutty.
Eddie Murphy
Sherman Klump / Buddy Love / Granny Klump / Mama Klump / Papa Klump / Young Papa Klump / Ernie Klump / Lance Perkins
Janet Jackson
Denise
Larry Miller
Dean Richmond
John Ales
Jason
Richard Gant
Denise's Father
Anna Maria Horsford
Denise's Mother
Melinda McGraw
Leanne Guilford
Jamal Mixon
Ernie Klump, Jr.
Gabriel Williams
Issac
Chris Elliott
Restaurant Manager
Duffy Taylor
Restaurant Trainee
Earl Boen
Dr. Knoll
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